Signals tracked for Hygia Reagents Inc
The public records we read for Hygia Reagents, ordered by how close each sits to the moment a small program has to bring its media, buffers and cryopreservation medium in from outside with a CoA and a batch record. Every account on the Accounts tab came out of one of these classes, and the class is named there.
How we rank a record
Two questions decide a record's value: how close is it to the point where a bench-made buffer has to become a qualified ancillary material, and is the program small enough to want a custom lot at Hygia's size. A funded aim that names GMP production beats a funding announcement; an announcement beats a job post.
One record is a lead. Two independent records at the same program, a state award and a federal renewal, or a funded aim and a plant opening, is a window.
Closest to the first GMP lot
Three to twelve months outGrant and award text where the sponsor itself says, in writing, what manufacturing step the money funds and when it started.
Federal award aim naming GMP production or engineering runs
An NIH SBIR, STTR or U44 abstract whose specific aims say the sponsor will establish GMP production, run engineering runs, or adapt its process toward cGMP. Dated by the award notice and project start.
From this screenThe Tiny Cargo Company: award started 2026-07-01 to establish GMP production of its milk exosome drug in its own Roanoke plant.
State preclinical award with a manufacturing activity
A CIRM preclinical development award whose applicant-written activities include finalizing the manufacturing process or GMP release strategy, read from the board review summary and dated by the board vote.
From this screenSavanna Biotherapeutics: CIRM board approved $12,993,456 on 2025-12-11; first activity is to finalize the manufacturing process at a university biomanufacturing center.
Award committed to a company that did not exist last year
A state or federal award approved for a company incorporated within the year. No incumbent supplier can exist; every material is chosen for the first time. Conditional until work starts.
From this screenEVADE Therapeutics: incorporated April 2026, $12,480,000 CIRM award approved 2026-06-25, status Pre-Active.
Window opening later
Twelve to twenty-four months outPrograms at the bench-to-qualified transition whose GMP step is funded for a later phase. Timed and held, not sent.
Phase I award that defers cGMP to Phase II
An STTR or SBIR Phase I whose aim is to adapt the process toward cGMP, with scale-up and engineering runs in a Phase II not yet awarded.
From this screenAgnos Therapeutics: STTR Phase I started 2026-08-01 to adapt an iPSC retinal-cell process toward cGMP, with an academic GMP partner in Los Angeles.
Academic program with a state award and a distant IND
A university or health-system lab funded for preclinical development with an IND several years out. In Hygia's existing customer class; the medium chosen now is the one qualified later.
From this screenScripps Health SCORE, San Diego: $12.7 million CIRM award announced 2026-04-13, IND targeted at the end of the grant.
Confirming only
Never lead with theseRegistry stage changes
A ClinicalTrials.gov record moving to not-yet-recruiting with a start date months out. Useful to date a window, but old registrations get pushed forward for years, so a record is checked against the sponsor's other filings before it counts.
Process development, MSAT and quality postings
A live posting confirms a program is standing up a process and who will own supplier qualification. It never originates a window and never carries a card alone.
Company site and conference profiles
A self-published IND date or manufacturing claim, dated by the event it appeared at. Used to corroborate an award, never to carry one.
What each account arrives with
- Company and the record that surfaced it, linked to the primary source with its date
- The person who owns the batch record, with title, and a checked work email where one exists
- The suggested opening line and the correction, so outreach never claims more than the record shows
Contact records are delivered in full, validation method and date included.
Record classes describe categories of public record and the cadence we read them on. Per-account claims live on the Accounts tab with their sources.